Acetone → HCID 22902368, compound

Participants

Reaction Conditions

Reaction Steps

7.3 g of 3-methoxyphenylthiobenzamide [preparation similar to Example 65 B)] were dissolved in 50 ml acetone and cooled to -20° C. in a nitrogen atmosphere. A solution of 4 ml oxalyl chloride in 40 ml acetone were added slowly dropwise to this solution. Then it was stirred for 1 hour at 20° C. The crystals that settled out were drawn off and the mother liquor concentrated to approximately one-third of the original volume. A further crystal fraction was obtained. In all, 5 g of 2-(3-methoxyphenyl)-1,3-thiazole -4,5-dione were obtained as a yellow solid.

Provenance & Evidence