Formaldehyde → HCID 19429349, compound

HRID 1078399Notes

Reaction equation

HRID 1078399 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([NH:11][CH2:12][CH2:13][CH2:14][N:15]2[CH:19]=[CH:18][N:17]=[CH:16]2)([CH3:10])[CH3:9])=[CH:4][CH:3]=1.[CH2:20]=O>C(O)=O>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([N:11]([CH2:12][CH2:13][CH2:14][N:15]2[CH:19]=[CH:18][N:17]=[CH:16]2)[CH3:20])([CH3:10])[CH3:9])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 712FormaldehydeHCID 9863253HCID 9863253, compound

Product 1

HCID 19429349HCID 19429349, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

In a similar manner to Example 90, N-[1-(4-chlorophenyl)-1-methylethyl]-3-(imidazol-1-yl)propylamine was reacted with formaldehyde and formic acid to give N-[1-(4-chlorophenyl)-1-methylethyl]-3-(imidazol-1-yl)-N-methylpropylamine, b.p. 170° C. (0.03 mmHg).

Sources & evidence

ORD record
ord-de0f6bc605ca42bc9e2887400a40456c
Source dataset
uspto-grants-1996_08
Patent number
US05547972

Reaction notes

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