Acetyl chloride → HCID 10297882, compound

Participants

Reaction Steps

2.42 g (5.87 mmol) of the alcohol obtained in Example 12 in 12 ml of pyridine are treated with 0.63 ml of acetyl chloride for 30 min. The reaction medium is poured into ice cold water, and extracted with ethyl acetate. The organic phase is washed with water, dried over magnesium sulphate and evaporated to give, after recrystallization from the ethyl acetate/hexane mixture, 1.67 g (63%) of a product which melts at 251° C.

Provenance & Evidence