Sodium Hydroxide → HCID 10763649, compound

Participants

Reaction Steps

3 g (7.2 mol) of methyl 4-[(Z)-2-(3-(1-adamantyl)-4-methoxyphenyl)propenyl]benzoate are treated with 4 g of sodium hydroxide in 50 ml of methanol and refluxed for 2 h 30min. After evaporation, the reaction medium is treated under the conditions described in Example 1(b). After recrystallization from absolute ethanol, 2.4 g (84%) of 4-[(Z)-2-(3-(1-adamantyl)-4-methoxyphenyl)propenyl]benzoic acid are isolated, which acid melts at 267° C.

Provenance & Evidence