HCID 10521715, compound → HCID 10617602, compound

Participants

Reaction Steps

28.82 g (0.083 mol) of 3-(1-methylcyclohexyl)-4-tert-butyldimethylsilyloxybenzoic acid, in 300 ml ether, are treated at -20° C. under nitrogen, with 0.166 mol of methyllithium (1.6M in ether). The reaction mixture is stirred under nitrogen overnight and it is then treated as for Example 25(a). After filtration of the residue on silica, 22 g (76%) of the expected product are isolated in the form of a yellow oil.

Provenance & Evidence