HCID 10506399, compound → HCID 10789247, compound

Participants

Reaction Steps

2.67 g (5 mmol) of the ester obtained in Example 42, in solution in 50 ml of dioxane, are stirred under a hydrogen pressure of 7 bar for 7 h at room temperature and then for 1 h at 50° C. in the presence of 800 mg of palladium on carbon (10%). After the same treatment as in Example 5 followed by a recrystallization from the ethanol/water mixture, 1.78 g (81%) of the expected derivative are isolated, which derivative melts at 262.4° C.

Provenance & Evidence