Carbon Dioxide → HCID 54517257, compound

Participants

Reaction Steps

130 ml of tetrahydrofuran are introduced into a 1 l reactor which is cooled with a mixture of ice and salt and, under an argon atmosphere, 5 g (0.132 mol) of lithium aluminium hydride are added, followed by dropwise addition of 20.73 g (0.0825 mol) of ethyl (±)-6-methoxy-3,4-dihydro-2H-1,4-benzoxazine-3-acetate dissolved in 130 ml of tetrahydrofuran, and the mixture is stirred for 1.5 h. The reactor is cooled with a mixture of cardice and acetone, 40 ml of water and 20 ml of 1N sodium hydroxide are added dropwise and stirring is continued for 0.5 h.

Provenance & Evidence