HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1078567Generated: November 3, 2026
Ethyl 4-bromo-2-butenoate → HCID 54263662, compound
https://huagongshe.com/reaction/1078567
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl 4-bromo-2-butenoate | HCID 98102 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | 2,2,2-Trifluoro-N-(2-hydroxy-5-nitrophenyl)acetamide | HCID 19428103 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 54263662 | HCID 54263662 | — |
Reaction Steps
220 ml of ethanol are introduced into a 1 l three-necked flask, with magnetic stirring, cooled to 0° C., and 3 g (0.133 mol) of sodium are added slowly, in small portions, followed by successive dropwise addition of 22.29 g (0.088 mol) of N-(2-hydroxy-5-nitrophenyl)trifluoroacetamide and 22.65 g (0.088 mol) of 75% pure ethyl 4-bromo-2-butenoate, and the mixture is heated at reflux for 3 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05550125 |
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| Source dataset | uspto-grants-1996_08 |
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| ORD ID | ord-a9f00e59d32143649cd6c67b884ed6b3 |
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| Source note | uspto-grants-1996_08 |
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