1-(2-Methoxyphenyl)piperazine → HCID 19428170, compound

HRID 1078576Notes

Reaction equation

HRID 1078576 reaction equation
Cl[CH2:2][CH2:3][C:4]1[C:5](=[O:18])[O:6][C:7]2[CH:14]=[C:13]([O:15][CH3:16])[C:12]([OH:17])=[CH:11][C:8]=2[C:9]=1[CH3:10].[CH3:19][O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[N:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>C(O)C.C(Cl)(Cl)Cl>[OH:17][C:12]1[C:13]([O:15][CH3:16])=[CH:14][C:7]2[O:6][C:5](=[O:18])[C:4]([CH2:3][CH2:2][N:30]3[CH2:29][CH2:28][N:27]([C:22]4[CH:23]=[CH:24][CH:25]=[CH:26][C:21]=4[O:20][CH3:19])[CH2:32][CH2:31]3)=[C:9]([CH3:10])[C:8]=2[CH:11]=1

Participants

4

Reactant 2

HCID 13461-(2-Methoxyphenyl)piperazineHCID 19428147HCID 19428147, compound

Product 1

HCID 19428170HCID 19428170, compoundYield 14%

Reagents, catalysts & solvents 1

HCID 21889567Chloroform ethanolSolvent

Procedure

Process A; starting materials: 3-(2-chloroethyl)-6-hydroxy-7-methoxy-4-methyl-2H-1-benzopyran-2-one (Example 27) and 1-(2-methoxyphenyl)piperazine; yield 14%; m.p. 235°-237° C. (from ethanol/chloroform).

Sources & evidence

ORD record
ord-01ec5a0f2cdf4030ae67739a2f29841e
Source dataset
uspto-grants-1996_08
Patent number
US05550129

Reaction notes

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