N-(2-Methoxyphenyl)piperazine hydrochloride → HCID 19428159, compound

HRID 1078582Notes

Reaction equation

HRID 1078582 reaction equation
Cl[CH2:2][CH2:3][C:4]1[C:5](=[O:21])[O:6][C:7]2[CH:14]=[C:13]([O:15][CH3:16])[C:12]([O:17][CH:18]([CH3:20])[CH3:19])=[CH:11][C:8]=2[C:9]=1[CH3:10].Cl.[CH3:23][O:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][C:26]=1[N:31]1[CH2:36][CH2:35][NH:34][CH2:33][CH2:32]1>C(O)C>[CH3:16][O:15][C:13]1[C:12]([O:17][CH:18]([CH3:20])[CH3:19])=[CH:11][C:8]2[C:9]([CH3:10])=[C:4]([CH2:3][CH2:2][N:34]3[CH2:33][CH2:32][N:31]([C:26]4[CH:27]=[CH:28][CH:29]=[CH:30][C:25]=4[O:24][CH3:23])[CH2:36][CH2:35]3)[C:5](=[O:21])[O:6][C:7]=2[CH:14]=1

Participants

4

Reactant 2

HCID 9899402N-(2-Methoxyphenyl)piperazine hydrochlorideHCID 19428144HCID 19428144, compound

Product 1

HCID 19428159HCID 19428159, compoundYield 54%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Process A; starting materials: 3-(2-chloroethyl)-7-methoxy-4-methyl-6-(1-methylethoxy)-2H-1-benzopyran-2-one (Example 30) and 1-(2-methoxyphenyl)piperazine hydrochloride; yield 54%; m.p. 123°-125° C. (from ethanol).

Sources & evidence

ORD record
ord-ab7a2da67cc6466190bf5471adc1e8c6
Source dataset
uspto-grants-1996_08
Patent number
US05550129

Reaction notes

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