1-(2-Fluorophenyl)piperazine → HCID 19428163, compound

HRID 1078596Notes

Reaction equation

HRID 1078596 reaction equation
Cl[CH2:2][CH2:3][C:4]1[C:5](=[O:19])[O:6][C:7]2[CH:14]=[C:13]([O:15][CH3:16])[CH:12]=[C:11]([O:17][CH3:18])[C:8]=2[C:9]=1[CH3:10].[F:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[N:27]1[CH2:32][CH2:31][NH:30][CH2:29][CH2:28]1>C(O)C>[F:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][C:22]=1[N:27]1[CH2:32][CH2:31][N:30]([CH2:2][CH2:3][C:4]2[C:5](=[O:19])[O:6][C:7]3[CH:14]=[C:13]([O:15][CH3:16])[CH:12]=[C:11]([O:17][CH3:18])[C:8]=3[C:9]=2[CH3:10])[CH2:29][CH2:28]1

Participants

4

Reactant 2

HCID 705291-(2-Fluorophenyl)piperazineHCID 194281613-(2-chloroethyl)-5,7-dimethoxy-4-methyl-2H-1-benzopyran-2-one

Product 1

HCID 19428163HCID 19428163, compoundYield 42%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Process B; starting materials: 3-(2-chloroethyl)-5,7-dimethoxy-4-methyl-2H-1-benzopyran-2-one (Example 39) and 1-(2-fluorophenyl)piperazine; yield 42%; m.p. 152°-153° C. (from ethanol).

Sources & evidence

ORD record
ord-c647f2fcf4bb4cd89824da09cb2b3720
Source dataset
uspto-grants-1996_08
Patent number
US05550129

Reaction notes

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