Ethanol → HCID 19428146, compound

Participants

Reaction Steps

30.0 g (127 mmol) of 7,8-dihydroxy-3-(2-hydroxyethyl)-4-methyl-2H-1-benzopyran-2-one (Example 52), 52.7 g (381 mmol) of potassium carbonate and 43.6 g (280 mmol) of ethyl iodide are stirred under reflux for 50 hours in 800 ml of ethanol. The solution is evaporated, extracted with chloroform, and the organic phase is washed with water, dried with Na2SO4, and re-evaporated. Yield 21.0 g (57%); m.p. 130°-131° C. (from isopropanol).

Provenance & Evidence