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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1078782Generated: October 27, 2026

Benzylamine → 2,3-Dihydro-5-methoxy-6-(phenylmethoxy)-2-(phenylmethyl)-1H-isoindole

https://huagongshe.com/reaction/1078782

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzylamineHCID 7504—
ReactantBis(chloromethyl)-4-methoxy-5-(phenylmethoxy)benzeneHCID 10591097—
Product2,3-Dihydro-5-methoxy-6-(phenylmethoxy)-2-(phenylmethyl)-1H-isoindoleHCID 10736303—

Reaction Steps

The procedure of Example 26 is repeated using 1.0 g of bis(chloromethyl)-4-methoxy-5-(phenylmethoxy)benzene and 0.6 mL of benzyl amine. This affords 0.74 g of the desired product as a beige solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05550149
Source datasetuspto-grants-1996_08
ORD IDord-ef9660011c50445a8a6e5e9aed7d3884
Source noteuspto-grants-1996_08