Diethylphosphite → HCID 86749763, compound

Participants

Reaction Steps

11.3 g (81.9 mmol) of diethyl phosphite and 2 ml of 1,8-diazabicyclo[5.4.0]undecene (DBU) are initially introduced into 200 ml of anhydrous tetrahydrofuran, a solution of 15.0 g (81.9 mmol) of dodecylsulfoxyacetone in 50 ml of tetrahydrofuran is added dropwise, and the mixture is subsequently refluxed for 8 hours. When the solution has cooled, it is washed twice using saturated sodium chloride solution and dried over sodium sulfate, and the solvent is distilled off, finally at 0.5 mbar and 60° C. bath temperature.

Provenance & Evidence