4-Iodotoluene → HCID 19428733, compound

HRID 1079107Notes

Reaction equation

[C:1]([NH:4][C:5]1[C:10]([CH3:11])=[CH:9][C:8]([C:12]2[CH:21]=[C:20]([CH3:22])[C:15]([NH:16][C:17](=O)[CH3:18])=[CH:14][C:13]=2[CH3:23])=[C:7]([CH3:24])[CH:6]=1)(=O)[CH3:2].[CH3:25][C:26]1[CH:31]=CC(I)=[CH:28][CH:27]=1>>[CH3:24][C:7]1[CH:6]=[CH:5][C:1]([NH:4][C:5]2[C:10]([CH3:11])=[CH:9][C:8]([C:12]3[CH:21]=[C:20]([CH3:22])[C:15]([NH:16][C:17]4[CH:28]=[CH:27][C:26]([CH3:25])=[CH:31][CH:18]=4)=[CH:14][C:13]=3[CH3:23])=[C:7]([CH3:24])[CH:6]=2)=[CH:2][CH:8]=1

Participants

Reactant 2

HCID 122074-Iodotoluene

HCID 343850N,N'-diacetyl-2,5,2',5'-tetramethylbenzidine

Product 1

HCID 19428733HCID 19428733, compound

Procedure

According to the same manner as that described in Synthesis Example 1, 16.19 of N,N'-diacetyl-2,5,2',5'-tetramethylbenzidine was reacted with 21.8 g of 4-methyliodobenzene to give N,N'-bis(4-methylphenyl)-2,5,2',5'-tetramethylbenzidine. Further, 12.0 g of N,N'-bis(4-methylphenyl)-2,5,2',5'-tetramethylbenzidine was reacted with 13.0 g of 4-tert-butyliodobenzene according to the same manner as that described in Synthesis Example 1 to give N,N'-bis(4-methylphenyl)-N,N'-bis(4-tert-butylphenyl)-2,5,2',5'-tetramethylbenzidine of the formula (4-a) (9.0 g, yield: 27.1%).

Sources & evidence

ORD record: ord-ab54d70ad5fb4f4c8293c5a1e1c6a479
Source dataset: uspto-grants-1996_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05550290

Reaction notes

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