1,4-Butanediol → 2-(4-Nitrobenzyl)-1,3,2-dioxaphosphepan-2-oxide

HRID 1079309Notes

Reaction equation

HRID 1079309 reaction equation
[N+:1]([C:4]1[CH:14]=[CH:13][C:7]([CH2:8][P:9](=[O:12])([OH:11])[OH:10])=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH2:15](O)[CH2:16][CH2:17][CH2:18]O>>[N+:1]([C:4]1[CH:14]=[CH:13][C:7]([CH2:8][P:9]2(=[O:10])[O:11][CH2:18][CH2:17][CH2:16][CH2:15][O:12]2)=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 80641,4-ButanediolHCID 5180708(4-Nitro-benzyl)-phosphonic acid

Product 1

HCID 189280782-(4-Nitrobenzyl)-1,3,2-dioxaphosphepan-2-oxide

Procedure

With 4-nitrobenzylphosphonic acid and 1,4-butanediol, the same procedure as in Reference Example 11 was followed, to yield 2-(4-nitrobenzyl)-1,3,2-dioxaphosphepane-2-oxide, which was then recrystallized from ethanol-hexane to yield colorless needles having a melting point of 136° to 137° C.

Sources & evidence

ORD record
ord-b930de0c15d8425e85c8f293e4f6f39c
Source dataset
uspto-grants-1996_12
Patent number
US05580863

Reaction notes

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