HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Indazol-5-amine → 7-fluoro-4-(1H-indazol-5-ylamino)quinazoline hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Indazol-5-amine | HCID 88012 | — |
| Reactant | 4-Chloro-7-fluoroquinazoline | HCID 16227013 | — |
| Product | 7-fluoro-4-(1H-indazol-5-ylamino)quinazoline hydrochloride | HCID 23366766 | 70% |
Reaction Steps
Using an analogous procedure to that described in Example 5, 4-chloro-7-fluoroquinazoline was reacted with 5-amino-1H-indazole to give 7-fluoro-4-(1H-indazol-5-ylamino)quinazoline hydrochloride in 70% yield, m.p. >300° C.;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05580870 |
| Source dataset | uspto-grants-1996_12 |
| ORD ID | ord-51c83cdf842844728318ea6195b74ad7 |
| Source note | uspto-grants-1996_12 |