Allyl bromide → HCID 131719735, compound

Participants

Reaction Steps

A solution of 4-tert-butylcarbonyl-7α-methoxy-3-methyl-2-(1-methyl-1,2,3,4-tetrazol-5-yl)thio-3-cephem 1,1-dioxide (100 mg) and allyl bromide (0.061 ml) was treated, at room temperature, with triethylamine (0.037 ml). After 2 hrs the reaction was over (TLC monitoring). Dilution with dichloromethane, washing with brine, drying over Na2SO4 and removal of the solvent left a residue which afforded the title compound as a white solide (60 mg) after flash chromatography.

Provenance & Evidence