4-Morpholinecarbonyl chloride → Methyl 1-(morpholin-4-ylcarbonyl)-5-[4-(trifluoromethoxy)phenyl]piperidine-3-carboxylate
Reaction equation
[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([CH:10]2[CH2:11][CH:12]([C:16](=[O:17])[O:18][CH3:19])[CH2:13][NH:14][CH2:15]2)[cH:8][cH:9]1)([F:20])[F:21].[O:22]1[CH2:23][CH2:24][N:25]([C:28](=[O:29])[Cl:30])[CH2:26][CH2:27]1>>[F:1][C:2]([O:3][c:4]1[cH:5][cH:6][c:7]([CH:10]2[CH2:11][CH:12]([C:16](=[O:17])[O:18][CH3:19])[CH2:13][N:14]([C:28]([N:25]3[CH2:24][CH2:23][O:22][CH2:27][CH2:26]3)=[O:29])[CH2:15]2)[cH:8][cH:9]1)([F:20])[F:21]Participants
3
Sources & evidence
- ORD record
- ord-55d388a5d84e46acacc14b60afe60839
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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