2-(Ethoxymethylene)propanedinitrile → HCID 53746681, compound

HRID 1080396Notes

Reaction equation

HRID 1080396 reaction equation
[F:1][CH:2]([F:12])[O:3][C:4]1[N:8]([CH3:9])[N:7]=[C:6]([NH:10][NH2:11])[CH:5]=1.C(O[CH:16]=[C:17]([C:20]#[N:21])[C:18]#[N:19])C>C(O)C>[NH2:21][C:20]1[N:10]([C:6]2[CH:5]=[C:4]([O:3][CH:2]([F:1])[F:12])[N:8]([CH3:9])[N:7]=2)[N:11]=[CH:16][C:17]=1[C:18]#[N:19]

Participants

4

Reactant 2

HCID 671522-(Ethoxymethylene)propanedinitrileHCID 15767488HCID 15767488, compound

Product 1

HCID 53746681HCID 53746681, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

22.5 g (0.13 mol) 5-Difluoromethoxy-3-hydrazino-1-methylpyrazole was dissolved in 310 ml ethanol and treated with 5.4 g (0.13 mol) ethoxymethylenemalononitrile. After the mixture had been heated under reflux for one hour it was cooled. The precipitate was suction filtered and washed with a small amount of ethanol.

Workup

  1. temperatureAfter the mixture had been heated
  2. temperatureunder reflux for one hour it
  3. temperaturewas cooled
  4. filtrationfiltered
  5. washwashed with a small amount of ethanol

Sources & evidence

ORD record
ord-309280781abf4f3bb5f93607bb2c64dc
Source dataset
uspto-grants-1996_12
Patent number
US05580986

Reaction notes

Loading…