Methylhydrazine → 3-Amino-1-methyl-5-methylsulfanyl-1H-pyrazole-4-carbonitrile

HRID 1080412Notes

Reaction equation

HRID 1080412 reaction equation
CS[C:3](=[C:6]([C:9]#[N:10])[C:7]#[N:8])[S:4][CH3:5].[CH3:11][NH:12][NH2:13]>O>[NH2:8][C:7]1[C:6]([C:9]#[N:10])=[C:3]([S:4][CH3:5])[N:12]([CH3:11])[N:13]=1

Participants

4

Reactant 2

HCID 6061MethylhydrazineHCID 992292-(Bis(methylsulfanyl)methylidene)propanedinitrile

Product 1

HCID 28195393-Amino-1-methyl-5-methylsulfanyl-1H-pyrazole-4-carbonitrile

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

9.63 g (56.6 mmol) [Bis(methylmercapto)methylene]malononitrile was suspended in 50 ml water and treated with 3.7 ml (67.9 mmol) methylhydrazine. The mixture was heated at boiling for 1 hour, the reaction solution cooled, the precipitate suction filtered and recrystallised from ethanol.

Workup

  1. temperatureThe mixture was heated
  2. temperaturethe reaction solution cooled
  3. filtrationthe precipitate suction filtered
  4. customrecrystallised from ethanol

Sources & evidence

ORD record
ord-8858edf247984298af7eacafee2e71ce
Source dataset
uspto-grants-1996_12
Patent number
US05580986

Reaction notes

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