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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 10808Generated: October 26, 2026

2-Methylpyrrolidine → racemic [4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl][3-n itro-4-(2-methyl-1-pyrrolidinyl)phenyl]methanone

https://huagongshe.com/reaction/10808

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-MethylpyrrolidineHCID 13003—
Reactant[4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl](4-chloro-3-nitrophenyl)methanoneHCID 10162409—
Productracemic [4-Amino-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-5-thiazolyl][3-n itro-4-(2-methyl-1-pyrrolidinyl)phenyl]methanoneHCID 21958928—

Reaction Steps

This compound was prepared from the compound of Example 15 and racemic 2-methylpyrrolidine (Alfa Aesar) by the procedure used in Example 57. Mass spectrum (ES) MH+=522.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07094896B2
Source datasetuspto-grants-2006_08
ORD IDord-f71ea8aaf3d74f99a567d56fac4f7b4d
Source noteuspto-grants-2006_08