HRID10809

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2724002

(2R)-2-Amino-4-methyl-1-pentanol

C6H15NO

结构：CN1CCN(c2ccc(Nc3nc(N)c(C(=O)c4ccc(Cl)c([N+](=O)[O-])c4)s3)cc2)CC1

HCID10162409

未命名化合物

PRODUCTS

生成物

结构：CC(C)C[C@H](CO)Nc1ccc(C(=O)c2sc(Nc3ccc(N4CCN(C)CC4)cc3)nc2N)cc1[N+](=O)[O-]

HCID60092052

未命名化合物

PROCEDURE

实验过程

This compound was prepared from the compound of Example 15 and (R)-2-amino-4-methyl-1-pentanol (Aldrich) by the procedure used in Example 57. Mass spectrum (ES) MH+=554.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-bf0a53130d38412282e165d28ddfe4be
来源数据集: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07094896B2
来源说明: uspto-grants-2006_08

反应 SMILES

[NH2:1][C:2]1[N:3]=[C:4]([NH:19][C:20]2[CH:25]=[CH:24][C:23]([N:26]3[CH2:31][CH2:30][N:29]([CH3:32])[CH2:28][CH2:27]3)=[CH:22][CH:21]=2)[S:5][C:6]=1[C:7]([C:9]1[CH:14]=[CH:13][C:12](Cl)=[C:11]([N+:16]([O-:18])=[O:17])[CH:10]=1)=[O:8].[NH2:33][C@H:34]([CH2:37][CH:38]([CH3:40])[CH3:39])[CH2:35][OH:36]>>[NH2:1][C:2]1[N:3]=[C:4]([NH:19][C:20]2[CH:25]=[CH:24][C:23]([N:26]3[CH2:31][CH2:30][N:29]([CH3:32])[CH2:28][CH2:27]3)=[CH:22][CH:21]=2)[S:5][C:6]=1[C:7]([C:9]1[CH:14]=[CH:13][C:12]([NH:33][C@@H:34]([CH2:35][OH:36])[CH2:37][CH:38]([CH3:40])[CH3:39])=[C:11]([N+:16]([O-:18])=[O:17])[CH:10]=1)=[O:8]