1-[2-(4-Iodophenoxy)ethyl]-4-methylpiperidin-4-ol → 1-(2-{4-[3-Fluoro-5-(4-methylcyclohex-1-enyl)pyridin-2-ylethynyl]phenoxy}ethyl)-4-methylpiperidin-4-ol
Reaction equation
[C:1](#[CH:2])[c:3]1[n:4][cH:5][c:6]([C:10]2=[CH:11][CH2:12][CH:13]([CH3:16])[CH2:14][CH2:15]2)[cH:7][c:8]1[F:9].[I:17][c:18]1[cH:19][cH:20][c:21]([O:22][CH2:23][CH2:24][N:25]2[CH2:26][CH2:27][C:28]([OH:31])([CH3:32])[CH2:29][CH2:30]2)[cH:33][cH:34]1>>[C:1](#[C:2][c:18]1[cH:19][cH:20][c:21]([O:22][CH2:23][CH2:24][N:25]2[CH2:26][CH2:27][C:28]([OH:31])([CH3:32])[CH2:29][CH2:30]2)[cH:33][cH:34]1)[c:3]1[n:4][cH:5][c:6]([C:10]2=[CH:11][CH2:12][CH:13]([CH3:16])[CH2:14][CH2:15]2)[cH:7][c:8]1[F:9]Participants
3
Sources & evidence
- ORD record
- ord-72b1fb1eb1c1454b99a6c002d518b79a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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