Coumarin, 4-hydroxy-3-phenyl- → HCID 22856981, compound

HRID 1081255Notes

Reaction equation

HRID 1081255 reaction equation
OC1C2C(=CC=CC=2)OC(=O)C=1C1C=CC=CC=1.[CH2:19]([O:26][C:27]([NH:29][C@H:30]([C:34]([OH:36])=[O:35])[CH:31]([CH3:33])[CH3:32])=[O:28])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1.[NH2:37][C@H:38]([C:40]([OH:42])=[O:41])[CH3:39].BrCC(CBr)=O.[NH2:49][C@H:50]([C:55]([OH:57])=[O:56])[CH2:51][C:52]([OH:54])=[O:53]>>[CH2:19]([O:26][C:27]([NH:29][C@H:30]([C:34]([OH:36])=[O:35])[CH:31]([CH3:33])[CH3:32])=[O:28])[C:20]1[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=1.[NH2:37][C@H:38]([C:40]([OH:42])=[O:41])[CH3:39].[NH2:49][C@H:50]([C:55]([OH:57])=[O:56])[CH2:51][C:52]([OH:54])=[O:53]

Participants

3

Reactant 2

HCID 54688870Coumarin, 4-hydroxy-3-phenyl-HCID 131719750HCID 131719750, compound

Product 1

HCID 22856981HCID 22856981, compound

Procedure

(mass spectrum m/z 672 (M+), 628, 587, 531) was prepared as described above from 4-hydroxy-3-phenylcoumarin and N-benzyloxycarbonyl-L-valine-L-alanine-L-aspartic acid bromomethyl ketone.

Workup

  1. custom(mass spectrum m/z 672 (M+), 628, 587, 531) was prepared

Sources & evidence

ORD record
ord-6745871a050a4be5807019eff655f3b4
Source dataset
uspto-grants-1996_12
Patent number
US05585357

Reaction notes

Loading…