HCID 67705210, compound → HCID 67705238, compound

HRID 1081256Notes

Reaction equation

HRID 1081256 reaction equation
[CH3:1][C:2]1([CH3:23])[C:10]2([CH3:11])[CH:5]([CH:6]([OH:12])[CH2:7][CH2:8][CH2:9]2)[CH2:4][CH:3]1[CH2:13][CH2:14][O:15][CH2:16][CH2:17][CH2:18][C:19]([OH:22])([CH3:21])[CH3:20].[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl>[CH3:1][C:2]1([CH3:23])[C:10]2([CH3:11])[CH:5]([C:6](=[O:12])[CH2:7][CH2:8][CH2:9]2)[CH2:4][CH:3]1[CH2:13][CH2:14][O:15][CH2:16][CH2:17][CH2:18][C:19]([OH:22])([CH3:21])[CH3:20]

Participants

4

Reactant 2

HCID 67705210HCID 67705210, compoundHCID 178418287HCID 178418287, compound

Product 1

HCID 67705238HCID 67705238, compoundYield 77.4%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

260 mg (0.80 mmol) of 48 is reacted with 240 mg (1.12 mmol) of pyridinium chlorochromate in 16 ml of methylene chloride analogously to 30., and 201 mg of the title compound is obtained as colorless oil.

Sources & evidence

ORD record
ord-ead5b6763c674e1fa714747025100d60
Source dataset
uspto-grants-1996_12
Patent number
US05585368

Reaction notes

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