HCID 67705323, compound → HCID 86750066, compound

HRID 1081257Notes

Reaction equation

HRID 1081257 reaction equation
[CH3:1][C:2]1([CH3:25])[C:10]2([CH3:11])[CH:5]([CH:6]([OH:12])[CH2:7][CH2:8][CH2:9]2)[CH2:4][CH:3]1[CH2:13][CH2:14][O:15][CH2:16][CH2:17][CH2:18][C:19]([CH2:23][CH3:24])([OH:22])[CH2:20][CH3:21].[Cr](Cl)([O-])(=O)=O.[NH+]1C=CC=CC=1>C(Cl)Cl>[CH3:25][C:2]1([CH3:1])[C:10]2([CH3:11])[CH:5]([C:6](=[O:12])[CH2:7][CH2:8][CH2:9]2)[CH2:4][CH:3]1[CH2:13][CH2:14][O:15][CH2:16][CH2:17][CH2:18][C:19]([CH2:23][CH3:24])([OH:22])[CH2:20][CH3:21]

Participants

4

Reactant 2

HCID 67705323HCID 67705323, compoundHCID 178418287HCID 178418287, compound

Product 1

HCID 86750066HCID 86750066, compoundYield 73.1%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

251 mg (0.71 mmol) of 49 is reacted with 212 mg (0.99 mmol) of pyridinium chlorochromate in 16 ml of methylene chloride analogously to 30., and 183 mg of the title compound is obtained as colorless oil.

Sources & evidence

ORD record
ord-fdfde4e30ad6430390a067eb69862e02
Source dataset
uspto-grants-1996_12
Patent number
US05585368

Reaction notes

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