1-Benzyl-4-(2-chloroethyl)piperazine → 5'-Phenyl-1'-[2-[4-(phenylmethyl)-1-piperazinyl]ethyl]spiro[1,3-dioxolane-2,3'-[3H]indol]-2'(1'H)-one

Participants

Role	Name	HCID	Charge
Reactant	1-Benzyl-4-(2-chloroethyl)piperazine	HCID 4741634	—
Reactant	5'-phenylspiro[1,3-dioxolane-2,3'-[3H]indol]-2'(1'H)-one	HCID 23363879	—
Product	5'-Phenyl-1'-[2-[4-(phenylmethyl)-1-piperazinyl]ethyl]spiro[1,3-dioxolane-2,3'-[3H]indol]-2'(1'H)-one	HCID 23363864	—

Reaction Steps

Following the general method of Example 14, 5'-phenylspiro[1,3-dioxolane-2,3'-[3H]indol]-2'(1'H)-one and 1-(2-chloroethyl)-4-(phenylmethyl)piperazine were reacted together to give the title compound. 13C Nmr (d6 -acetone) 173.9, 144.5, 141.0, 139.6, 136.6, 130.7, 129.7, 129.6, 128.9, 127.9, 127.6, 127.3, 126.2, 124.1, 110.6, 102.7, 66.5, 63.3, 55.6, 54.0, 53.8 and 38.0 ppm.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US05585378
Source dataset	uspto-grants-1996_12
ORD ID	ord-8d96650a012141159de05dcd2a24156a
Source note	uspto-grants-1996_12