1H,3H-furo(3,4-c)pyridine-1,3-dione → HCID 12574287, compound

HRID 1081336Notes

Reaction equation

HRID 1081336 reaction equation
[CH:1]1[C:6]2[C:7]([O:9][C:10](=[O:11])[C:5]=2[CH:4]=[N:3][CH:2]=1)=[O:8].[CH3:12][C:13]1[CH:18]=[CH:17][C:16]([Mg]Br)=[CH:15][CH:14]=1>>[CH3:12][C:13]1[CH:18]=[CH:17][C:16]([C:7]([C:6]2[CH:1]=[CH:2][N:3]=[CH:4][C:5]=2[C:10]([OH:9])=[O:11])=[O:8])=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 2783981H,3H-furo(3,4-c)pyridine-1,3-dioneHCID 178418370HCID 178418370, compound

Product 1

HCID 12574287HCID 12574287, compound

Procedure

Employing 3,4-pyridinecarboxylic anhydride (10.0 g) and 4-methylphenyl magnesium bromide, substantially the same reaction and process as in Reference Example 2 Step 1 were conducted to give 4-(4-methylbenzoyl)-3-pyridinecarboxylic acid as colorless crystals.

Sources & evidence

ORD record
ord-67e517b3420b4c15ae8d02ea6f30eed4
Source dataset
uspto-grants-1996_12
Patent number
US05585385

Reaction notes

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