HCID 67554107, compound → HCID 178455888, compound

HRID 1081380Notes

Reaction equation

HRID 1081380 reaction equation
[NH:1]1[C:5]([C:6]2[CH:17]=[CH:16][C:9]([CH2:10][S:11][CH2:12][C:13]([OH:15])=O)=[CH:8][CH:7]=2)=[N:4][N:3]=[N:2]1.Cl.[CH3:19][O:20][C:21](=[O:50])[C@H:22]([CH2:46][CH2:47][S:48][CH3:49])[NH:23][C:24](=[O:45])[CH2:25][N:26]([CH2:38][C@@H:39]([NH2:44])[C@@H:40]([CH3:43])[CH2:41][CH3:42])[CH2:27][C:28]1[C:37]2[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=2)[CH:31]=[CH:30][CH:29]=1>>[CH3:19][O:20][C:21](=[O:50])[C@H:22]([CH2:46][CH2:47][S:48][CH3:49])[NH:23][C:24](=[O:45])[CH2:25][N:26]([CH2:38][C@@H:39]([NH:44][C:13](=[O:15])[CH2:12][S:11][CH2:10][C:9]1[CH:8]=[CH:7][C:6]([C:5]2[NH:1][N:2]=[N:3][N:4]=2)=[CH:17][CH:16]=1)[C@@H:40]([CH3:43])[CH2:41][CH3:42])[CH2:27][C:28]1[C:37]2[C:32](=[CH:33][CH:34]=[CH:35][CH:36]=2)[CH:31]=[CH:30][CH:29]=1

Participants

3

Reactant 2

HCID 67554107HCID 67554107, compoundHCID 178526045HCID 178526045, compound

Product 1

HCID 178455888HCID 178455888, compound

Procedure

Following the procedure described for Example 1, Step G, [4-(1H-tetrazol-5-yl)benzylthio]acetic acid was coupled with N-(2(S)-amino-3(S)-methylpentyl)-N-(1-naphthylmethyl)-glycyl-methionine methyl ester hydrochloride to give the title compound.

Sources & evidence

ORD record
ord-74f61ca608164277ab1759a91ac2e7d5
Source dataset
uspto-grants-1996_12
Patent number
US05585359

Reaction notes

Loading…