HRID1081381

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID177085

(Benzyloxy)acetyl chloride

C9H9ClO2

结构：CCC(C)[C@H](N)CN(CC(=O)N[C@@H](CCSC)C(=O)OC)Cc1cccc2ccccc12.Cl

HCID67553617

未命名化合物

PRODUCTS

生成物

结构：CC[C@H](C)[C@@H](CN(CC(=O)N[C@@H](CCSC)C(=O)OC)Cc1cccc2ccccc12)NC(=O)COCc1ccccc1

HCID53875035

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from N-[2(S)-amino-3-methylpentyl)-N-(1-naphthylmethyl)-glycyl-methionine methyl ester hydrochloride (Example 1, Step E) and benzyloxyacetyl chloride (Aldrich) under standard conditions.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4d5e2bf32e7d4e7a8172aaa8e48729bd
来源数据集: uspto-grants-1996_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05585359
来源说明: uspto-grants-1996_12

反应 SMILES

Cl.[CH3:2][O:3][C:4](=[O:33])[C@H:5]([CH2:29][CH2:30][S:31][CH3:32])[NH:6][C:7](=[O:28])[CH2:8][N:9]([CH2:21][C@@H:22]([NH2:27])[CH:23]([CH3:26])[CH2:24][CH3:25])[CH2:10][C:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13][CH:12]=1.[CH2:34]([O:41][CH2:42][C:43](Cl)=[O:44])[C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1>>[CH3:2][O:3][C:4](=[O:33])[C@H:5]([CH2:29][CH2:30][S:31][CH3:32])[NH:6][C:7](=[O:28])[CH2:8][N:9]([CH2:21][C@@H:22]([NH:27][C:43](=[O:44])[CH2:42][O:41][CH2:34][C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1)[C@@H:23]([CH3:26])[CH2:24][CH3:25])[CH2:10][C:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:14]=[CH:13][CH:12]=1