N-Methyl-tert-butylamine → HCID 23364249, compound

Participants

Reaction Steps

A mixture of 0.5 g of the compound obtained in EXAMPLE 16 step A), 1 ml of N-methyl-tert-butylamine and 20 ml of DCM is stirred for 2 hours at RT. The solvent is evaporated off under vacuum and the residue is chromatographed on silica using a DCM/AcOEt mixture (95/5; v/v) as the eluent to give 0.13 g of the expected product after crystallization from an iso ether/ AcOEt mixture (65/35; v/v). M.p.=208° C.

Provenance & Evidence