162141-56-2 → HCID 23364286, compound

HRID 1081514Notes

Reaction equation

HRID 1081514 reaction equation
[CH:1]1([N:6]2[C:10]3[CH:11]=[C:12]([O:15][CH2:16][CH3:17])[CH:13]=[CH:14][C:9]=3[NH:8][C:7]2=[O:18])[CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:19][O:20][C:21]([C:23]1[CH:28]=[CH:27][C:26]([S:29](Cl)(=[O:31])=[O:30])=[C:25]([O:33][CH3:34])[CH:24]=1)=[O:22]>>[CH:1]1([N:6]2[C:10]3[CH:11]=[C:12]([O:15][CH2:16][CH3:17])[CH:13]=[CH:14][C:9]=3[N:8]([S:29]([C:26]3[CH:27]=[CH:28][C:23]([C:21]([O:20][CH3:19])=[O:22])=[CH:24][C:25]=3[O:33][CH3:34])(=[O:31])=[O:30])[C:7]2=[O:18])[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 23364278162141-56-2HCID 53763179HCID 53763179, compound

Product 1

HCID 23364286HCID 23364286, compoundYield 72.7%

Procedure

This compound is prepared by the procedure described in EXAMPLE 107 step A) starting from 1 g of 3- cyclopentyl-5-ethoxy-1,3-dihydro-2H-benzimidazol-2-one and 1.2 g of 4-methoxycarbonyl-2-methoxybenzenesulfonyl chloride. It is chromatographed on silica using a DCM/AcOEt mixture (95/5; v/v) as the eluent to give 1.4 g of the expected product. M.p.=151° C.

Workup

  1. customThis compound is prepared by the procedure
  2. customIt is chromatographed on silica using a DCM/AcOEt mixture (95/5; v/v) as the eluent

Sources & evidence

ORD record
ord-b28310d94e074d9ab240811b58416b31
Source dataset
uspto-grants-1996_12
Patent number
US05585394

Reaction notes

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