(2,6-Dichlorophenyl)acetonitrile → 2,4-Diamino-5-(2,6-dichlorophenyl)-6-methoxymethyl-pyrimidine

HRID 1081593Notes

Reaction equation

HRID 1081593 reaction equation
[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[CH:14]=[C:13](Cl)[CH:12]=[C:11](Cl)[C:10]=2[Cl:17])=[C:4]([CH2:18][O:19][CH3:20])[N:3]=1.[Cl:21]C1C=CC=C(Cl)C=1CC#N>>[NH2:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([C:9]2[C:14]([Cl:21])=[CH:13][CH:12]=[CH:11][C:10]=2[Cl:17])=[C:4]([CH2:18][O:19][CH3:20])[N:3]=1

Participants

3

Reactant 2

HCID 76678(2,6-Dichlorophenyl)acetonitrileHCID 117391082,4-Diamino-5-(2,3,5-trichlorophenyl)-6-methoxymethylpyrimidine

Product 1

HCID 197050722,4-Diamino-5-(2,6-dichlorophenyl)-6-methoxymethyl-pyrimidine

Procedure

This compound was prepared in an analogous manner to the compound of Example 2 from 2,6-dichlorophenylacetonitrile (Aldrich), mp. 204°-207° C.

Sources & evidence

ORD record
ord-fa06ef23488446f7a6bf21e1237890dc
Source dataset
uspto-grants-1996_12
Patent number
US05587380

Reaction notes

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