HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 54135753, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4-Chloro-2,3-dimethyl-1-oxidopyridin-1-ium | HCID 9877446 | — |
| Reactant | 2-(4-Methyl-1,3-thiazol-5-yl)ethane-1-thiol | HCID 18690003 | — |
| Product | HCID 54135753 | HCID 54135753 | 79% |
Reaction Steps
Following the procedure described in Example Aa), the reaction of 4-chloro-2,3-dimethylpyridine N-oxide with 5-(2-mercaptoethyl)-4-methylthiazole in the presence of sodium hydride gives 2,3-dimethyl-4-[2-(4-methyl-5-thiazolyl)-ethylthio]pyridine N-oxide; m.p.: 135°-137° C (yield: 79%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05587389 |
| Source dataset | uspto-grants-1996_12 |
| ORD ID | ord-527e5380bdce41c7beddefbf8ed0949e |
| Source note | uspto-grants-1996_12 |