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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1081794Generated: October 25, 2026

3-(2,4-Dimethoxyphenyl)prop-2-enoic acid → 1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2,4-dimethoxyphenyl)ethenyl)-1,3-dipropyl-, (E)-

https://huagongshe.com/reaction/1081794

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(2,4-Dimethoxyphenyl)prop-2-enoic acidHCID 85636—
Reactant5,6-Diamino-1,3-dipropyl-2,4(1H,3H)-pyrimidinedioneHCID 5098605—
Product1H-Purine-2,6-dione, 3,7-dihydro-8-(2-(2,4-dimethoxyphenyl)ethenyl)-1,3-dipropyl-, (E)-HCID 6448780—

Reaction Steps

Substantially the same procedure as in Reference Example 1 was repeated using 3.0 g (13.3 mmol) of 5,6-diamino-1,3-dipropyluracil and 3.04 g (14.60 mmol) of 2,4-dimethoxycinnamic acid. Then, the resultant crude crystals were recrystallized from dioxane/water to give 1.26 g (yield of Compound 24 as white crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05587378
Source datasetuspto-grants-1996_12
ORD IDord-9d4c0e86202d4b80ac578a8639886af8
Source noteuspto-grants-1996_12