Benzoyl Peroxide → HCID 15837892, compound

Participants

Reaction Steps

1-(4-Chloro-2-methylphenoxy)naphthalene (1.8 g) from Example 1 was dissolved in carbon tetrachloride (10 ml), followed by addition of NBS (1.2 g) and a catalytic amount of benzoyl peroxide under reflux for 2 hours. After leaving the solution to stand at room temperature, insoluble materials were filtered off, and the filtrate was concentrated under reduced pressure. The residue was purified by chromatography on a silica gel column (hexane:ether=99:1) to give the title compound (900 mg; 39%).

Provenance & Evidence