Dimethylformamide → HCID 54314587, compound

Participants

Reaction Steps

6 g (0.026 mol) of 1-(2-chloro-3-nitrophenoxy)propan-2-amine, 3.6 g (0.026 mol) of potassium carbonate and 20 ml of N,N-dimethylformamide are heated at 110° C. with stirring overnight. The reaction mixture is poured into water and extracted 3 times with ether. The organic phase is recovered, washed with water, dried and the solvent evaporated to dryness. There are obtained 4 g of product in the form of a crystalline residue which is used as is in the following stage.

Provenance & Evidence