4-Chlorobenzaldehyde → HCID 54075018, compound

Participants

Reaction Steps

A mixture of 3,4-dimethyoxyphenylacetonitrile (1.77 g, 10.0 mmol, purchased from Tokyo Kasei,) and 4-chlorobenzaldehyde (1.4 g, 10.0 mmol, purchased from Tokyo Kasei) in 5 ml of ethanol was heated to dissolve. Two drops of 20% aqueous sodium hydroxide solution was then added and the reaction mixture was stirred over night. The resultant reaction mass was crushed in ethanol. The precipitate was Collected and washed with ethanol then with hexane, and dried to give 2.39 g (yield: 79.7%) of α-cyano-3,4-dimethoxy-4'-chlorostilbene as a greenish yellow crystalline.

Provenance & Evidence