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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1082851Generated: October 25, 2026

2-Acetyl-5-bromothiophene → HCID 178466103, compound

https://huagongshe.com/reaction/1082851

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Acetyl-5-bromothiopheneHCID 79335—
Reactant1H-Imidazole, 1-(1-methylethyl)-HCID 10176113—
ReagentPotassium TrimethylacetateHCID 23662159—
Catalyst1-(Dicyclohexylphosphino)-2-phenyl-1H-indoleHCID 121235231—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178466103HCID 17846610321.87%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-af525be5bf6f49ea85992eeb0ac17136
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide