HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1082897Generated: October 30, 2026
1-Methyl-1H-imidazole-4-carbonitrile → ethyl 4-(4-cyano-1-methyl-1H-imidazol-5-yl)-1-ethyl-1H-pyrrole-2-carboxylate
https://huagongshe.com/reaction/1082897
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Methyl-1H-imidazole-4-carbonitrile | HCID 2795115 | — |
| Reactant | Ethyl 4-bromo-1-ethyl-1H-pyrrole-2-carboxylate | HCID 78918332 | — |
| Reagent | Potassium Trimethylacetate | HCID 23662159 | — |
| Catalyst | 2-(Dicyclohexylphosphino)-2'-(dimethylamino)biphenyl | HCID 2734217 | — |
| Catalyst | HCID 178455864 | HCID 178455864 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | ethyl 4-(4-cyano-1-methyl-1H-imidazol-5-yl)-1-ethyl-1H-pyrrole-2-carboxylate | HCID 117937785 | 5.88% |
| Internal standard | 4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenyl | HCID 74195 | — |
Provenance & Evidence
| DOI | 10.26434/chemrxiv |
|---|
| Source dataset | Pd-catalyzed C-H arylation of imidazole with aryl bromide |
|---|
| ORD ID | ord-efe934bfb1124e2b95d968517bdd75f0 |
|---|
| Source note | Pd-catalyzed C-H arylation of imidazole with aryl bromide |
|---|
