HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1082950Generated: November 4, 2026
1-Bromo-2-fluorobenzene → 5-(2-Fluorophenyl)-1-methylimidazole-4-carbonitrile
https://huagongshe.com/reaction/1082950
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Bromo-2-fluorobenzene | HCID 61259 | — |
| Reactant | 1-Methyl-1H-imidazole-4-carbonitrile | HCID 2795115 | — |
| Reagent | Potassium Trimethylacetate | HCID 23662159 | — |
| Catalyst | 9-[2-(Diethylphosphino)phenyl]-9H-carbazole | HCID 118878622 | — |
| Catalyst | HCID 178455864 | HCID 178455864 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | 5-(2-Fluorophenyl)-1-methylimidazole-4-carbonitrile | HCID 84117446 | 77.38% |
| Internal standard | 4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenyl | HCID 74195 | — |
Provenance & Evidence
| DOI | 10.26434/chemrxiv |
|---|
| Source dataset | Pd-catalyzed C-H arylation of imidazole with aryl bromide |
|---|
| ORD ID | ord-e071f2e7420548f59146a1373382482d |
|---|
| Source note | Pd-catalyzed C-H arylation of imidazole with aryl bromide |
|---|
