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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1083073Generated: October 30, 2026

1-Methylimidazole → HCID 178481234, compound

https://huagongshe.com/reaction/1083073

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylimidazoleHCID 1390—
Reactant3-Bromo-5-(trifluoromethyl)pyridineHCID 11127991—
ReagentPotassium TrimethylacetateHCID 23662159—
CatalystTris(furan-2-yl)phosphaneHCID 521585—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178481234HCID 17848123473.55%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-81e7584ca2304287bc348fd51929fede
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide