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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1083161Generated: October 30, 2026

Benzofuran, 5-bromo- → HCID 178506399, compound

https://huagongshe.com/reaction/1083161

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran, 5-bromo-HCID 90015—
Reactant1-(Difluoromethyl)-2-phenyl-1H-imidazoleHCID 53485766—
ReagentPotassium TrimethylacetateHCID 23662159—
Catalyst2-(Dicyclohexylphosphino)-2'-(dimethylamino)biphenylHCID 2734217—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178506399HCID 17850639977.61%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-860e73ba459c4b2fbf244f24312dfc56
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide