Dichloromethane → 1-(2-Fluoro-4-nitro-phenyl)-pyrrolidine-2-carbaldehyde

HRID 108322Notes

Reaction equation

HRID 108322 reaction equation
[Cl:23][CH2:24][Cl:25].[F:1][c:2]1[c:3]([N:11]2[CH:12]([CH2:16][OH:17])[CH2:13][CH2:14][CH2:15]2)[cH:4][cH:5][c:6]([N+:8](=[O:9])[O-:10])[cH:7]1.[O-:18][I+3:19]([O-:20])([O-:21])[O-:22]>>[F:1][c:2]1[c:3]([N:11]2[CH:12]([CH:16]=[O:17])[CH2:13][CH2:14][CH2:15]2)[cH:4][cH:5][c:6]([N+:8](=[O:9])[O-:10])[cH:7]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 167232PeriodateHCID 18416155(1-(2-Fluoro-4-nitrophenyl)pyrrolidin-2-yl)methanol

Product 1

HCID 593003601-(2-Fluoro-4-nitro-phenyl)-pyrrolidine-2-carbaldehyde

Sources & evidence

ORD record
ord-620afe8c2c1a4451bed5abf58d0650d0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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