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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1083333Generated: October 29, 2026

1-Bromo-2-fluorobenzene → HCID 178432950, compound

https://huagongshe.com/reaction/1083333

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Bromo-2-fluorobenzeneHCID 61259—
Reactant1-Benzyl-2,4-dimethyl-1H-imidazoleHCID 14744973—
ReagentPotassium TrimethylacetateHCID 23662159—
CatalystTris(o-methoxyphenyl)phosphineHCID 78464—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178432950HCID 1784329501.23%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-fd8a1dbd652843449096ca4f11326491
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide