Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1083365Generated: October 31, 2026

3-Bromo-5-(trifluoromethyl)pyridine → HCID 178432951, compound

https://huagongshe.com/reaction/1083365

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-5-(trifluoromethyl)pyridineHCID 11127991—
Reactant1-Benzyl-2,4-dimethyl-1H-imidazoleHCID 14744973—
ReagentPotassium TrimethylacetateHCID 23662159—
Catalyst2'-[(1,1-Dimethylethyl)phenylphosphino]-N2,N2,N6,N6-tetramethyl-[1,1'-biphenyl]-2,6-diamineHCID 121237783—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178432951HCID 17843295112.3%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-1656ea06a14749449f8459a0c8d6e6f1
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide