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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1083370Generated: October 29, 2026

3-Bromo-5-(trifluoromethyl)pyridine → HCID 178432951, compound

https://huagongshe.com/reaction/1083370

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Bromo-5-(trifluoromethyl)pyridineHCID 11127991—
Reactant1-Benzyl-2,4-dimethyl-1H-imidazoleHCID 14744973—
ReagentPotassium TrimethylacetateHCID 23662159—
CatalystTriphenylphosphineHCID 11776—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178432951HCID 1784329512.2%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-a6350e2cfd3e4127a8a6f241f877af47
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide