Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1083464Generated: October 31, 2026

1H-Imidazole, 1-(1-methylethyl)- → HCID 178456433, compound

https://huagongshe.com/reaction/1083464

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Imidazole, 1-(1-methylethyl)-HCID 10176113—
Reactant3-Bromo-5-(trifluoromethyl)pyridineHCID 11127991—
ReagentPotassium TrimethylacetateHCID 23662159—
CatalystTricyclohexylphosphineHCID 75806—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178456433HCID 1784564330.86%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-56db199d745149628f1b16dbc49a010f
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide