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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1083465Generated: October 31, 2026

1H-Imidazole, 1-(1-methylethyl)- → HCID 178456433, compound

https://huagongshe.com/reaction/1083465

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Imidazole, 1-(1-methylethyl)-HCID 10176113—
Reactant3-Bromo-5-(trifluoromethyl)pyridineHCID 11127991—
ReagentPotassium TrimethylacetateHCID 23662159—
Catalyst1,3,5,7-Tetramethyl-6-phenyl-2,4,8-trioxa-6-phosphaadamantaneHCID 53427790—
CatalystHCID 178455864HCID 178455864—
SolventDimethylacetamideHCID 31374—
ProductHCID 178456433HCID 17845643326.42%
Internal standard4,4'-Bis(1,1-dimethylethyl)-1,1'-biphenylHCID 74195—

Reaction Conditions

Temperature120 °C

Provenance & Evidence

DOI10.26434/chemrxiv
Source datasetPd-catalyzed C-H arylation of imidazole with aryl bromide
ORD IDord-65c75285c2ac47c18523f9a0b82bcada
Source notePd-catalyzed C-H arylation of imidazole with aryl bromide